When you shop for inositol powder you'll run into two camps: powders that are myo-inositol only, and powders that blend myo-inositol with d-chiro-inositol at 40:1. To make the choice concrete, we've compared one popular product from each camp: Health & Balance Vitamins' myo-only powder and our own Regüsk Inositol Powder. Full transparency: we make Regüsk Inositol Powder, and we've used only what each brand publishes.
The quick answer
- Choose a myo-only powder like Health & Balance if you want a higher dose of a single, well-studied form of inositol in one scoop, with nothing else added.
- Choose a 40:1 powder like Regüsk Inositol Powder if you want both forms of inositol together, plus active folate and magnesium, in a flavoured daily sachet.
Myo-only vs 40:1: what's the difference?
Myo-inositol and d-chiro-inositol are the two forms of inositol studied most. Your body makes d-chiro from myo, and healthy blood carries them at roughly 40 parts myo to 1 part d-chiro. A 2019 trial comparing several ratios found 40:1 performed best of the combinations it tested (Nordio et al., 2019).
That doesn't make myo-only powders a poor choice. Myo-inositol on its own has plenty of research behind it, and the 2023 international PCOS guideline concluded that the evidence isn't strong enough to recommend one specific type, dose or combination of inositol over another (Teede et al., 2023; Fitz et al., 2024). In other words, this is a preference, and neither camp can claim to have settled it.
Health & Balance vs Regüsk Inositol Powder: side by side
Based on each brand's website, October 2026. Always check the current label before buying.
| Regüsk Inositol Powder | Health & Balance Myo-Inositol Powder | |
|---|---|---|
| Form of inositol | Myo + d-chiro at 40:1 | Myo-inositol only |
| Per serving | 1,100mg myo + 27.5mg d-chiro | 3,000mg myo |
| Format | Pre-measured 4g sachet | Tub with scoop |
| Directions | One sachet daily | One scoop in any liquid, morning or mid-afternoon |
| Also contains | L-methylfolate 440mcg, magnesium glycinate, ashwagandha, chaste berry, maca, vitamin B6 | Nothing added |
| Flavour | Blackberry lemon | Unflavoured |
| Sizes | 30 sachets, or a 90-sachet bundle | 33, 66 or 99 servings |
| Vegan | Yes | Yes |
Where the two inositol powders differ
1. How much inositol you get
Health & Balance gives you 3g of myo-inositol in one scoop, almost three times the inositol in a Regüsk sachet. If a higher dose is what you want, the myo-only tub delivers it in a single serving.
2. One form or two
Regüsk Inositol Powder includes d-chiro-inositol at the 40:1 ratio. Health & Balance deliberately leaves it out. If you or your practitioner prefer myo-inositol on its own, that's a reason to choose the tub.
3. What else is in it
Health & Balance is one ingredient. Regüsk Inositol Powder adds active folate, magnesium glycinate and a small botanical blend, which suits women who would otherwise buy those separately. It also means Regüsk Inositol Powder isn't recommended during pregnancy or breastfeeding. More in why we add botanicals to inositol powder.
4. Scoop or sachet
Both are once a day, which makes either easy to stick with. The tub is cheaper per gram. The sachet is pre-measured, flavoured and easy to carry.
Which inositol powder should you choose?
- You want myo-inositol only: Health & Balance.
- You want the higher dose in one scoop: Health & Balance.
- You want a 40:1 blend with folate and magnesium: Regüsk Inositol Powder.
- You want flavour and no measuring: Regüsk Inositol Powder.
Comparing 40:1 options specifically? See our six-brand inositol powder comparison.
Try Regüsk Inositol Powder
40:1 myo and d-chiro inositol with active folate and magnesium, in one blackberry-lemon sachet a day. Shop Regüsk Inositol Powder with free shipping and a 100-day guarantee.
Sources
- Health & Balance Vitamins. Inositol: product page and FAQ. Accessed October 2026.
- Teede HJ, et al. Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2023;108(10):2447–2469. doi:10.1210/clinem/dgad463
- Fitz V, et al. Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines. J Clin Endocrinol Metab. 2024;109(6):1630–1655. doi:10.1210/clinem/dgad762
- Nordio M, Basciani S, Camajani E. The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios. Eur Rev Med Pharmacol Sci. 2019;23(12):5512–5521. PubMed
This article is for general information only and isn't medical advice. Regüsk Inositol Powder is a dietary supplement and is not intended to diagnose, treat, cure or prevent any disease. Health & Balance Vitamins is a trademark of its owner, and Regüsk is not affiliated with it. Comparison details were taken from the brand's website at the time of writing, so check the current label before buying. Talk to your healthcare professional before starting any supplement.